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Endothelial origin of mesenchymal stem cells

1 May 2011

Abstract excerpt

Mesenchymal stem/stromal cells (MSCs) are fibroblastoid cells capable of long-term expansion and skeletogenic differentiation. While MSCs are known to originate from neural crest and mesoderm, immediate mesodermal precursors that give rise to MSCs have not been characterized. Recently, using human embryonic stem cells (hESCs), we demonstrated that mesodermal MSCs arise from APLNR+ precursors with angiogenic...

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PMID: 21444996
DOI: 10.4161/cc.10.9.15345

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