Article
Characterization of the L683P mutation of SLC26A9 in Xenopus oocytes.
Biochimica et biophysica acta - 1 Jun 2011
Avella Martine, Borgese Franck, Ehrenfeld Jordi
Abstract excerpt
In the present study, we characterized a STAS-domain amino acid mutation of SLC26A9 having a significant impact on ion transport. We focused on the sole conserved L- leucine residue of the STAS domain identified among SLC26 members. We therefore characterized the L683P mutation of SLC26A9 in Xenopus oocytes by monitoring the protein functional expression (two-electrode technique for voltage-clamp analysis) and...
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