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Article

Circulating matrix γ-carboxyglutamate protein (MGP) species are refractory to vitamin K treatment in a new case of Keutel syndrome.

Journal of thrombosis and haemostasis : JTH - 1 Jun 2011

Cranenburg E C M, VAN Spaendonck-Zwarts K Y, Bonafe L, Mittaz Crettol L, Rödiger L A, Dikkers F G, VAN Essen A J, Superti-Furga A, Alexandrakis E, Vermeer C, Schurgers L J, Laverman G D

Abstract excerpt

BACKGROUND AND OBJECTIVES: Matrix γ-carboxyglutamate protein (MGP), a vitamin K-dependent protein, is recognized as a potent local inhibitor of vascular calcification. Studying patients with Keutel syndrome (KS), a rare autosomal recessive disorder resulting from MGP mutations, provides an opportunity to investigate the functions of MGP. The purpose of this study was (i) to investigate the phenotype and the...

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Source

Identifiers

PMID: 21435166
DOI: 10.1111/j.1538-7836.2011.04263.x

Genes

MGP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Circulating matrix γ-carboxyglutamate protein (MGP) species are refractory to vitamin K treatment in a new case of Keutel syndrome.PMID 21435166Read ↗

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