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Article

Rapid insulin-like growth factor-1-induced changes in granulosa cell thrombospondin-1 expression in vitro.

The Journal of reproduction and development - 1 Feb 2011

McGray A J Robert, Gingerich Timothy, Petrik James J, LaMarre Jonathan

Abstract excerpt

Thrombospondin-1 (TSP-1) is a large extracellular matrix-associated protein that is important for normal follicular development, is rapidly modulated during follicular growth and plays important roles in cellular proliferation and angiogenesis. TSP-1 mRNA is post-transcriptionally regulated, although the underlying mechanisms are largely unknown. Insulin-like growth factor-1 is a potent signalling molecule that...

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PMID: 21422735
DOI: 10.1262/jrd.10-045h

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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