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Article

Recombinant heteromeric phenylalanine monooxygenase and the oxygenation of carbon and sulfur substrates.

The Journal of pharmacy and pharmacology - 1 Apr 2011

Boonyapiwat Boontarika, Mitchell Stephen C, Steventon Glyn B

Abstract excerpt

OBJECTIVES: The aim of this investigation was to provide in-vitro enzyme kinetic data to support the hypothesis that the in-vivo heterozygous dominant phenotype for phenylalanine monooxygenase (hPAH) was responsible for the S-oxidation polymorphism in the metabolism of S-carboxymethyl-l-cysteine reported in humans. Using a dual-vector expression strategy for the co-production of wild-type and mutant human hPAH...

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Identifiers

PMID: 21401608
DOI: 10.1111/j.2042-7158.2010.01242.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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