Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Disruptive events in the life of prostate cancer.

Cancer cell - 8 Mar 2011

Brenner J Chad, Chinnaiyan Arul M

Abstract excerpt

Two recent reports in Nature provide evidence for increasingly complex "disruptive" molecular alterations that occur during prostate cancer progression. They shed light on the intricacy of genetic changes that modulate PTEN's control over the phosphoinositide 3-kinase pathway and prostate cancer progression, and identify new potential biomarkers and therapeutic targets.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptor Proteins, Signal Transducing
Share to Cyclin D1
Share to Disease Progression

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Guanylate Kinases

Share to Phosphatidylinositol 3-Kinases

Share to Prostatic Neoplasms

Share to PTEN Phosphohydrolase

Share to Repressor Proteins

Source

Identifiers

PMID: 21397854
DOI: 10.1016/j.ccr.2011.02.020

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Disruptive events in the life of prostate cancer.PMID 21397854Read ↗

Reprint of: The prostate cancer genome: Perspectives and potential.Semantic proximity Read ↗

The prostate cancer genome: perspectives and potential.Semantic proximity Read ↗

Dissecting Major Signaling Pathways throughout the Development of Prostate CancerSemantic proximity Read ↗

Prostate cancer, PI3K, PTEN and prognosis.Semantic proximity Read ↗

Interactions between key genes and pathways in prostate cancer progression and therapy resistanceSemantic proximity Read ↗

The PTEN Conundrum: How to Target PTEN-Deficient Prostate CancerSemantic proximity Read ↗

Genetic alterations in human prostate cancer: a review of current literature.Semantic proximity Read ↗

Molecular Pathways in Prostate CancerSemantic proximity Read ↗

Molecular pathways to prostate cancer.Semantic proximity Read ↗

Methodological aspects of the molecular and histological study of prostate cancer: focus on PTEN.Semantic proximity Read ↗

Molecular carcinogenesis of prostate cancer: potential clinical relevance and nursing implications.Semantic proximity Read ↗

Oncogenes and tumor suppressor genes in prostate cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.