Article
Disruptive events in the life of prostate cancer.
Cancer cell - 8 Mar 2011
Brenner J Chad, Chinnaiyan Arul M
Abstract excerpt
Two recent reports in Nature provide evidence for increasingly complex "disruptive" molecular alterations that occur during prostate cancer progression. They shed light on the intricacy of genetic changes that modulate PTEN's control over the phosphoinositide 3-kinase pathway and prostate cancer progression, and identify new potential biomarkers and therapeutic targets.
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