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Article

Impact of consanguineous marriages in GJB2-related hearing loss in the Iranian population: a report of a novel variant.

Genetic testing and molecular biomarkers - 1 Jan 2000

Mahdieh Nejat, Rabbani Bahareh, Shirkavand Atefeh, Bagherian Hamideh, Movahed Zahra Shahab, Fouladi Paanti, Rahiminejad Faezeh, Masoudifard Masoumeh, Akbari Mohammad Taghi, Zeinali Sirous

Abstract excerpt

Mutations in GJB2 and GJB6 genes are the main causes of autosomal recessive nonsyndromic hearing loss (ARNSHL) in many populations. Here, we investigated GJB2 and GJB6 mutations in 114 patients from 77 affected ARNSHL families including 54 consanguineous marriages and 23 nonrelative marriages in the Iranian population. Clinical studies and genetic counseling were performed for all families. GJB2 and GJB6 genes...

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Source

Identifiers

PMID: 21388256
DOI: 10.1089/gtmb.2010.0145

Genes

GJB6
GJB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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