Article
Polymorphisms of the β2-adrenergic receptor correlated to nocturnal asthma and the response of terbutaline nebulizer.
Pediatrics and neonatology - 1 Feb 2011
Lee Ming-Yung, Cheng Shin-Nan, Chen Shyi-Jou, Huang Hui-Ling, Wang Chih-Chien, Fan Hueng-Chuen
Abstract excerpt
BACKGROUND: Inhaled β(2)-adrenergic receptor (β(2)-AR) agonists are the mainstay of treatment of acute asthma. Polymorphisms of the β(2)-AR, especially codons 16, 27, and 164, may affect the functions of the receptor. This study was conducted to investigate whether different polymorphisms of the β(2)-AR are related to the treatment responses of an inhaled β(2)-AR agonist in children with nocturnal and...
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