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The preparation of an infectious full-length cDNA clone of Saffold virus

9 Mar 2011

Abstract excerpt

The pathogenicity of Saffold virus (SAFV) among humans still remains unclear, although it was identified as a novel human cardiovirus in 2007. In order to encourage the molecular pathogenetic studies of SAFV, we generated an infectious cDNA clone of SAFV type 3 (SAFV-3). The present study demonstrated that the synthesis of the full-length infectious RNA by T7 RNA polymerase was terminated by a homologous sequence...

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PMID: 21385468
DOI: 10.1186/1743-422x-8-110

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