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Article

A viral microRNA cluster strongly potentiates the transforming properties of a human herpesvirus.

PLoS pathogens - 1 Feb 2011

Feederle Regina, Linnstaedt Sarah D, Bannert Helmut, Lips Helge, Bencun Maja, Cullen Bryan R, Delecluse Henri-Jacques

Abstract excerpt

Epstein-Barr virus (EBV), an oncogenic human herpesvirus, induces cell proliferation after infection of resting B lymphocytes, its reservoir in vivo. The viral latent proteins are necessary for permanent B cell growth, but it is unknown whether they are sufficient. EBV was recently found to encode microRNAs (miRNAs) that are expressed in infected B cells and in some EBV-associated lymphomas. EBV miRNAs are...

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Share to B-Lymphocytes
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21379335
DOI: 10.1371/journal.ppat.1001294
PMCID: PMC3040666

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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