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[Cancer genome analysis through next-generation sequencing].

Gan to kagaku ryoho. Cancer & chemotherapy - 1 Jan 2011

Aburatani Hiroyuki

Abstract excerpt

Cancers are caused by the accumulation of genomic and epigenomic alterations. Particularly, genetic alterations, such as BCR-ABL translocation and EGFR mutation, which are present only in cancer cells, are the best therapeutic targets to date. The application of next-generation DNA sequencing technologies, including whole-genome, whole-exome and whole-transcriptome approaches, has brought substantial advances in...

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PMID: 21368453

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BCR
EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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