Article
Conversion of Mycobacterium smegmatis to a pathogenic phenotype via passage of epithelial cells during macrophage infection.
Medical microbiology and immunology - 1 Aug 2011
Kim Su-Young, Sohn Hosung, Choi Go-Eun, Cho Sang-Nae, Oh Taegwon, Kim Hwa-Jung, Whang Jake, Kim Jong-Seok, Byun Eui-Hong, Kim Woo Sik, Min Ki-Nam, Kim Jin Man, Shin Sung Jae
Abstract excerpt
Mycobacteria encounter many different cells during infection within their hosts. Although alveolar epithelial cells play an essential role in host defense as the first cells to be challenged upon contact with mycobacteria, they may contribute to the acquisition of mycobacterial virulence by increasing the expression of virulence or adaptation factors prior to being ingested by macrophages on the side of...
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