Article
Sex differences in urinary levels of several biological indicators of exposure: a human volunteer study.
Toxicology letters - 10 May 2011
Tomicic Catherine, Berode Michèle, Oppliger Anne, Castella Vincent, Leyvraz Fabienne, Praz-Christinaz Sophie-Maria, Danuser Brigitta
Abstract excerpt
The aim of the study was to quantify the variability on biological indicators of exposure between men and women for three well known solvents: methyl ethyl ketone, 1-methoxy-2-propanol and 1,1,1-trichloroethane. Another purpose was to explore the effect of selected CYP2E1 polymorphisms on the toxicokinetic profile. Controlled human exposures were carried out in a 12 m³ exposure chamber for each solvent...
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