Transcriptional sexual dimorphism during preimplantation embryo development and its consequences for developmental competence and adult health and disease.

Abstract excerpt

In adult tissues, sexual dimorphism is largely attributed to sex hormone effects, although there is increasing evidence for a major role of sex chromosome dosage. During preimplantation development, male and female embryos can display phenotypic differences that can only be attributed to the transcriptional differences resulting from their different sex chromosome complements. Thus, all expressed Y-linked genes...

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