Article
Transcriptomic effects of depleted uranium on acetylcholine and cholesterol metabolisms in Alzheimer's disease model.
Comptes rendus biologies - 1 Feb 2011
Lestaevel Philippe, Bensoussan Hélène, Racine Radjini, Airault Fabrice, Gourmelon Patrick, Souidi Maâmar
Abstract excerpt
Some heavy metals, or aluminium, could participate in the development of Alzheimer disease (AD). Depleted uranium (DU), another heavy metal, modulates the cholinergic system and the cholesterol metabolism in the brain of rats, but without neurological disorders. The aim of this study was to determine what happens in organisms exposed to DU that will/are developing the AD. This study was thus performed on a...
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