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Article

Epigenetic modifications associated with pathophysiological effects of lead exposure

12 Aug 2019

Abstract excerpt

Lead (Pb) exposure during different stages of development has demonstrated dose, duration, sex, and tissue-specific pathophysiological outcomes due to altered epigenetic regulation via (a) DNA methylation, (b) histone modifications, (c) miRNAs, and (d) chromatin accessibility. Pb-induced alteration of epigenetic regulation causes neurotoxic and extra-neurotoxic pathophysiological outcomes. Neurotoxic effects of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31402779
DOI: 10.1080/10590501.2019.1640581

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