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Article

Histone deacetylase inhibitor activity in royal jelly might facilitate caste switching in bees.

EMBO reports - 1 Mar 2011

Spannhoff Astrid, Kim Yong Kee, Raynal Noel J-M, Gharibyan Vazganush, Su Ming-Bo, Zhou Yue-Yang, Li Jia, Castellano Sabrina, Sbardella Gianluca, Issa Jean-Pierre J, Bedford Mark T

Abstract excerpt

Worker and queen bees are genetically indistinguishable. However, queen bees are fertile, larger and have a longer lifespan than their female worker counterparts. Differential feeding of larvae with royal jelly controls this caste switching. There is emerging evidence that the queen-bee phenotype is driven by epigenetic mechanisms. In this study, we show that royal jelly--the secretion produced by the...

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Identifiers

PMID: 21331099
DOI: 10.1038/embor.2011.9
PMCID: PMC3059907

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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