Article
What's the hype about CDK5RAP2?
Cellular and molecular life sciences : CMLS - 1 May 2011
Kraemer Nadine, Issa Lina, Hauck Stefanie C R, Mani Shyamala, Ninnemann Olaf, Kaindl Angela M
Abstract excerpt
Cyclin dependent kinase 5 regulatory subunit-associated protein 2 (CDK5RAP2) has gained attention in the last years following the discovery, in 2005, that recessive mutations cause primary autosomal recessive microcephaly. This disease is seen as an isolated developmental defect of the brain, particularly of the cerebral cortex, and was thus historically also referred to as microcephalia vera. Unraveling the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.