Cells from a vanished twin as a source of microchimerism 40 years later in a male with a scleroderma-like condition.

doi:10.4161/chim.1.2.14294

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Cells from a vanished twin as a source of microchimerism 40 years later in a male with a scleroderma-like condition.

1 Oct 2010

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We report the case of a 40-year-old man diagnosed with a scleroderma-like disease. Clinical similarities with graft versus host disease prompted initial testing for chimerism employing fluorescence in situ hybridization (FISH). Female cells were observed within peripheral blood mononuclear cells from the patient.Because maternal cells have been detected in healthy immunologically competent adults and patients...

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Cells from a vanished twin as a source of microchimerism 40 years later in a male with a scleroderma-like condition.

Abstract excerpt

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