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Article

β-catenin and Gli1 are prognostic markers in glioblastoma

15 Apr 2011

Abstract excerpt

Glioblastomas (GBMs), the most common primary malignancies of the central nervous system, are highly aggressive and heterogeneous, and remain a dramatic therapeutic challenge. Markers mirroring the complex molecular profile of GBMs that are predictive of patient outcomes are needed to define novel multi-targeted treatment strategies. Resistance to current GBM therapies is partly due to a subpopulation of...

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PMID: 21321483
DOI: 10.4161/cbt.11.8.14894

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