Article
Genome-wide analysis shows no genomic predictors of ovarian response to stimulation by exogenous FSH for IVF.
Reproductive biomedicine online - 1 Apr 2011
van Disseldorp Jeroen, Franke Lude, Eijkemans Rene, Broekmans Frank, Macklon Nick, Wijmenga Cisca, Fauser Bart
Abstract excerpt
The current proof of principle study explores the possibility that a genetic single-nucleotide polymorphism (SNP) profile is associated with ovarian response to standardized stimulation for IVF using exogenous FSH. Such a pharmacogenomic approach could aid in rendering ovarian stimulation for IVF more tailored to the patient, potentially improving the delicate balance between efficacy, side effects and chances...
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