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Article

Functional validation of new pathways in lipoprotein metabolism identified by human genetics

11 Feb 2011

Abstract excerpt

PURPOSE OF REVIEW: Recent genome-wide association studies (GWAS) have identified approximately 100 genomic loci that are associated with plasma lipid traits, two-thirds of which had never been previously associated with lipoprotein metabolism. Identification of the causal genes and variants, functional validation of these genes and biological pathways, and elucidation of molecular mechanisms is required and poses...

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Share to Diabetes, Cardiovascular Risks, and Lipoproteins
Share to Genetic Associations and Epidemiology
Share to Lipid metabolism and disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21311327
DOI: 10.1097/mol.0b013e32834469b3

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