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Article

Mechanisms of neurocognitive dysfunction and therapeutic considerations in tuberous sclerosis complex

4 Feb 2011

Abstract excerpt

PURPOSE OF REVIEW: Mendelian disorders that affect cognition provide a unique opportunity to study the mechanisms of neurodevelopmental disorders through the examination of genetic defects in animals and development of hypotheses that can be tested in human beings. Tuberous sclerosis complex (TSC) is a genetic disease that presents with epilepsy, autism, and intellectual disability. Here we review recent advances...

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PMID: 21301339
DOI: 10.1097/wco.0b013e32834451c4

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