Article
Obesity-associated genetic variants in young Asian Indians with the metabolic syndrome and myocardial infarction.
Cardiovascular journal of Africa - 1 Jan 2000
Ranjith N, Pegoraro R J, Shanmugam R
Abstract excerpt
OBJECTIVE: Associations between obesity-related polymorphisms and the metabolic syndrome in 485 young ( ≤ 45 Years) Asian Indian patients with acute myocardial infarction (AMI), and 300 matched controls were assessed. METHODS: Genetic variants included the adiponectin 45T→G and 276G→T, LEPR K109R and Q223R, MC4R-associated C→T and FTO A→T polymorphisms. RESULTS: The metabolic syndrome, as defined by NCEP ATP III...
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