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Article

Cone photoreceptor abnormalities correlate with vision loss in patients with Stargardt disease.

Investigative ophthalmology & visual science - 17 May 2011

Chen Yingming, Ratnam Kavitha, Sundquist Sanna M, Lujan Brandon, Ayyagari Radha, Gudiseva V Harini, Roorda Austin, Duncan Jacque L

Abstract excerpt

PURPOSE. To study the relationship between macular cone structure, fundus autofluorescence (AF), and visual function in patients with Stargardt disease (STGD). METHODS. High-resolution images of the macula were obtained with adaptive optics scanning laser ophthalmoscopy (AOSLO) and spectral domain optical coherence tomography in 12 patients with STGD and 27 age-matched healthy subjects. Measures of retinal...

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Identifiers

PMID: 21296825
DOI: 10.1167/iovs.10-6538
PMCID: PMC3109028

Genes

ABCA4
RPE

Provenance

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