Article
A genetic association study of single nucleotide polymorphisms in FGFR1OP2/wit3.0 and long-term atrophy of edentulous mandible.
PloS one - 19 Jan 2011
Suwanwela Jaijam, Lee Jaehoon, Lin Audrey, Ucer T Cemal, Devlin Hugh, Sinsheimer Janet, Garrett Neal R, Nishimura Ichiro
Abstract excerpt
BACKGROUND: After dental extraction, the external surface of alveolar bone undergoes resorption at various rates, and a group of patients develop excessive jawbone atrophy. Oral mucosa overlying the atrophied jawbone is unusually thin; therefore, we have hypothesized that excessive jawbone atrophy may be associated with abnormal oral mucosa contraction. FGFR1OP2/wit3.0, a cytoskeleton molecule initially...
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