Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Klebsiella pneumoniae outer membrane protein A is required to prevent the activation of airway epithelial cells.

The Journal of biological chemistry - 25 Mar 2011

March Catalina, Moranta David, Regueiro Verónica, Llobet Enrique, Tomás Anna, Garmendia Junkal, Bengoechea José A

Abstract excerpt

Outer membrane protein A (OmpA) is a class of proteins highly conserved among the Enterobacteriaceae family and throughout evolution. Klebsiella pneumoniae is a capsulated gram-negative pathogen. It is an important cause of community-acquired and nosocomial pneumonia. Evidence indicates that K. pneumoniae infections are characterized by a lack of an early inflammatory response. Data from our laboratory indicate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immune Evasion
Share to Interleukin-8

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Klebsiella Infections

Share to Mitogen-Activated Protein Kinase Kinases

Share to Nod1 Signaling Adaptor Protein

Share to Pneumonia, Bacterial

Share to Respiratory Mucosa

Share to Toll-Like Receptors

Source

Open in PubMed Open full text

Identifiers

PMID: 21278256
DOI: 10.1074/jbc.M110.181008
PMCID: PMC3060550

Genes

TLR2
NOD1
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Klebsiella pneumoniae outer membrane protein A is required to prevent the activation of airway epithelial cells.PMID 21278256Read ↗

Identification and Evaluation of Recombinant Outer Membrane Proteins as Vaccine Candidates Against Klebsiella pneumoniaeSemantic proximity Read ↗

The KbvR Regulator Contributes to Capsule Production, Outer Membrane Protein Biosynthesis, Antiphagocytosis, and Virulence in Klebsiella pneumoniae.Semantic proximity Read ↗

Human Airway Epithelial Cell Responses to Neisseria lactamica and Purified Porin via Toll-Like Receptor 2-Dependent SignalingSemantic proximity Read ↗

Outer Membrane Vesicles Derived from Klebsiella pneumoniae Influence the miRNA Expression Profile in Human Bronchial Epithelial BEAS-2B CellsSemantic proximity Read ↗

Klebsiella pneumoniae peptidoglycan-associated lipoprotein and murein lipoprotein contribute to serum resistance, antiphagocytosis, and proinflammatory cytokine stimulation.Semantic proximity Read ↗

Outer membrane Protein A plays a role in pathogenesis of Acinetobacter nosocomialis.Semantic proximity Read ↗

Outer membrane protein A of Acinetobacter baumannii regulates pulmonary inflammation through the TLR2-NF-κB pathwaySemantic proximity Read ↗

<i>Klebsiella pneumoniae C</i> o-infection Leads to Fatal Pneumonia in SARS-CoV-2-infected MiceSemantic proximity Read ↗

Streptococcus pneumoniae Evades Host Cell Phagocytosis and Limits Host Mortality Through Its Cell Wall Anchoring Protein PfbASemantic proximity Read ↗

The exopolysaccharide Poly-N-Acetyl-Glucosamine (PNAG) coats <i>Klebsiella pneumoniae in vivo</i>Semantic proximity Read ↗

Klebsiella pneumoniae OmpA confers resistance to antimicrobial peptides.Semantic proximity Read ↗

<i>Streptococcus pneumoniae</i> evades host cell phagocytosis and limits host mortality through its cell wall anchoring protein PfbASemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.