Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Persistence of γ-H2AX and 53BP1 foci in proliferating and non-proliferating human mammary epithelial cells after exposure to γ-rays or iron ions

27 Jan 2011

Abstract excerpt

PURPOSE: To investigate γ-H2AX (phosphorylated histone H2AX) and 53BP1 (tumour protein 53 binding protein No. 1) foci formation and removal in proliferating and non-proliferating human mammary epithelial cells (HMEC) after exposure to sparsely and densely ionising radiation under different cell culture conditions. MATERIAL AND METHODS: HMEC cells were grown either as monolayers (2D) or in extracellular matrix to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Cancer Treatment Studies
Share to DNA Repair Mechanisms
Share to Effects of Radiation Exposure

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21271785
DOI: 10.3109/09553002.2010.549535

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Persistence of γ-H2AX and 53BP1 foci in proliferating and non-proliferating human mammary epithelial cells after exposure to γ-rays or iron ionsPMID 21271785Read ↗

Characterizing the DNA Damage Response by Cell Tracking Algorithms and Cell Features Classification Using High-Content Time-Lapse AnalysisSemantic proximity Read ↗

Kinetics and dose-response of residual 53BP1/γ-H2AX foci: Co-localization, relationship with DSB repair and clonogenic survivalSemantic proximity Read ↗

3D-structured illumination microscopy reveals clustered DNA double-strand break formation in widespread γH2AX foci after high LET heavy-ion particle radiationSemantic proximity Read ↗

A Single Exposure to Low- or High-LET Radiation Induces Persistent Genomic Damage in Mouse Epithelial Cells In Vitro and in Lung Tissue.Semantic proximity Read ↗

Persistent DNA Double-Strand Breaks After Repeated Diagnostic CT Scans in Breast Epithelial Cells and LymphocytesSemantic proximity Read ↗

Radiosensitivity in breast cancer assessed by the histone γ-H2AX and 53BP1 fociSemantic proximity Read ↗

Recruitment of 53BP1 Proteins for DNA Repair and Persistence of Repair Clusters Differ for Cell Types as Detected by Single Molecule Localization MicroscopySemantic proximity Read ↗

Cumulative Dose from Recurrent CT Scans: Exploring the DNA Damage Response in Human Non-Transformed CellsSemantic proximity Read ↗

Chronic irradiation of human cells reduces histone levels and deregulates gene expressionSemantic proximity Read ↗

Induction and Repair of DNA DSB as Revealed by H2AX Phosphorylation Foci in Human Fibroblasts Exposed to Low- and High-LET Radiation: Relationship with Early and Delayed Reproductive Cell Death.Semantic proximity Read ↗

Quantification of radiation-induced DNA double strand break repair foci to evaluate and predict biological responses to ionizing radiationSemantic proximity Read ↗

Redox-Active Cerium Fluoride Nanoparticles Mitigate of Double-Stranded DNA Breakage and Modulate Gene Expression Due to Radiation Exposure<em> In Vitro</em>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.