Article
Alteration of PBP 3 entails resistance to imipenem in Listeria monocytogenes.
Antimicrobial agents and chemotherapy - 1 Sept 1990
Pierre J, Boisivon A, Gutmann L
Abstract excerpt
A mutant with decreased susceptibility to imipenem (IpR) was selected in vitro from a susceptible clinical isolate of Listeria monocytogenes (IpS). IpR exhibited decreased susceptibility to penicillin G (4 x MIC) and imipenem (16 x MIC) and increased susceptibility to cefotaxime (0.25 x MIC). Ele...
Topics
- Anti-Bacterial Agents
- Bacterial Proteins
- Carrier Proteins
- Cefotaxime
- Cephalothin
- Drug Resistance, Microbial
- Electrophoresis
- Hexosyltransferases
- Imipenem
- Listeria monocytogenes
- Membrane Proteins
- Microbial Sensitivity Tests
- Muramoylpentapeptide Carboxypeptidase
- Mutation
- Penicillin G
- Penicillin-Binding Proteins
- Peptidyl Transferases