Article
Alteration of PBP 3 entails resistance to imipenem in Listeria monocytogenes.
Antimicrobial agents and chemotherapy - 1 Sept 1990
Pierre J, Boisivon A, Gutmann L
Abstract excerpt
A mutant with decreased susceptibility to imipenem (IpR) was selected in vitro from a susceptible clinical isolate of Listeria monocytogenes (IpS). IpR exhibited decreased susceptibility to penicillin G (4 x MIC) and imipenem (16 x MIC) and increased susceptibility to cefotaxime (0.25 x MIC). Electrophoretic profiles of membrane proteins and penicillin-binding proteins (PBPs) were identical in the two strains;...
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