Article
Expressions of forkhead class box O 3a on crushed rat sciatic nerves and differentiated primary Schwann cells.
Cellular and molecular neurobiology - 1 May 2011
Wang Qiuhong, Wang Youhua, Zhou Zhengming, Lu Xiang, Cao Yi, Liu Yonghua, Yan Meijuan, He Fei, Pan Xia, Qian Xiaoli, Ji Yuhong, Yang Huiguang
Abstract excerpt
Forkhead box-containing protein, class O 3 a (FOXO3a), an Akt downstream target, plays an important role in peripheral nervous system. FOXO3a shares the ability to be inhibited and translocated from the nucleus on phosphorylation by proteins such as Akt/PKB in the PI3K signaling pathway. To elucidate the expression and possible function of FOXO3a in lesion and repair, we performed an acute sciatic nerve crush...
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