Article
Actin filament nucleation by the bacterial pathogen, Listeria monocytogenes.
The Journal of cell biology - 1 Dec 1990
Tilney L G, Connelly P S, Portnoy D A
Abstract excerpt
Shortly after Listeria is phagocytosed by a macrophage, it dissolves the phagosomal membrane and enters the cytoplasm. 1 h later, actin filaments coat the Listeria and then become rearranged to form a tail with which the Listeria moves to the macrophage surface as a prelude to spreading. If infected macrophages are treated with cytochalasin D, all the actin filaments associated with the Listeria break down...
Topics
- Actin Cytoskeleton
- Actins
- Animals
- Biopolymers
- Chloramphenicol
- Cytochalasin D
- Listeria monocytogenes
- Macrophages
- Mice
- Mutation