Article
Integrated profiling of microRNAs and mRNAs: microRNAs located on Xq27.3 associate with clear cell renal cell carcinoma.
PloS one - 30 Dec 2010
Zhou Liang, Chen Jiahao, Li Zhizhong, Li Xianxin, Hu Xueda, Huang Yi, Zhao Xiaokun, Liang Chaozhao, Wang Yong, Sun Liang, Shi Min, Xu Xiaohong, Shen Feng, Chen Maoshan, Han Zujing, Peng Zhiyu, Zhai Qingna, Chen Jing, Zhang Zhongfu, Yang Ruilin, Ye Jiongxian, Guan Zhichen, Yang Huanming, Gui Yaoting, Wang Jun, Cai Zhiming, Zhang Xiuqing
Abstract excerpt
BACKGROUND: With the advent of second-generation sequencing, the expression of gene transcripts can be digitally measured with high accuracy. The purpose of this study was to systematically profile the expression of both mRNA and miRNA genes in clear cell renal cell carcinoma (ccRCC) using massively parallel sequencing technology. METHODOLOGY: The expression of mRNAs and miRNAs were analyzed in tumor tissues and...
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