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HLA-G Expression in Human Embryonic Stem Cells and Preimplantation Embryos

20 Jan 2011

Abstract excerpt

Human leukocyte Ag-G, a tolerogenic molecule that acts on cells of both innate and adaptive immunity, plays an important role in tumor progression, transplantation, placentation, as well as the protection of the allogeneic fetus from the maternal immune system. We investigated HLA-G mRNA and protein expression in human embryonic stem cells (hESC) derived from the inner cell mass (ICM) of blastocysts. hESC...

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PMID: 21248264
DOI: 10.4049/jimmunol.1001081

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