Article
Genetic polymorphisms in placental transporters: implications for fetal drug exposure to oral antidiabetic agents.
Expert opinion on drug metabolism & toxicology - 1 Mar 2011
Pollex Erika K, Hutson Janine R
Abstract excerpt
INTRODUCTION: The prevalence of diabetes among women of childbearing age is increasing. This will inevitably increase the number of pregnancies complicated by diabetes. The management of diabetes mellitus often necessitates the use of oral antidiabetic drugs including biguanides, sulfonylureas, metiglinide analogs and thiazolidinediones. However, a significant concern with the use of these agents in pregnancy is...
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