Article
Biochemical and metabolomic phenotyping in the identification of a vitamin D responsive metabotype for markers of the metabolic syndrome.
Molecular nutrition & food research - 1 May 2011
O'Sullivan Aifric, Gibney Michael J, Connor Aine O, Mion Brian, Kaluskar Soniya, Cashman Kevin D, Flynn Albert, Shanahan Fergus, Brennan Lorraine
Abstract excerpt
SCOPE: Metabolic phenotyping promises to be a useful tool in human intervention studies. This study examined whether metabolic phenotyping could identify responders to vitamin D supplementation in terms of the metabolic syndrome. METHODS AND RESULTS: In a double-blind, randomised placebo-controlled dietary intervention subjects were assigned to receive 15 μg vitamin D(3) or placebo daily. Serum 25-hydroxyvitamin...
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