Article
Lack of association between plasminogen activator inhibitor type-1 (PAI-1) gene 4G/5G polymorphism and osteoarthritis.
Rheumatology international - 1 Jan 2012
Bayram Banu, Sayin Emrah, Erkasap Nilüfer, Onlü Harun, Ozkurt Mete, Sahin Fezan, Türkoğlu Züleyha
Abstract excerpt
This study was conducted in Turkish osteoarthritis patients to determine the frequency of 4G/5G polymorphism genotypes of plasminogen activator inhibitor type-1 gene and to examine the role of this polymorphism in osteoarthritis development. Genomic DNA obtained from 200 persons (140 patients with osteoarthritis and 60 healthy controls) was used in the study. DNA was amplified by polymerase chain reaction using...
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