Article
Co-regulatory expression quantitative trait loci mapping: method and application to endometrial cancer.
BMC medical genomics - 12 Jan 2011
Kompass Kenneth S, Witte John S
Abstract excerpt
BACKGROUND: Expression quantitative trait loci (eQTL) studies have helped identify the genetic determinants of gene expression. Understanding the potential interacting mechanisms underlying such findings, however, is challenging. METHODS: We describe a method to identify the trans-acting drivers of multiple gene co-expression, which reflects the action of regulatory molecules. This method-termed co-regulatory...
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