Head neck squamous cell carcinoma c‐Met⁺ cells display cancer stem cell properties and are responsible for cisplatin‐resistance and metastasis

Abstract excerpt

c-Met, the tyrosine kinase receptor for hepatocyte growth factor, is overexpressed in a variety of tumors in which it plays a central role in malignant transformation. Although c-Met has also been determined to be a critical signaling molecule in normal stem cell function, the potential role of c-Met as a single marker for cancer stem cells (CSCs) has not been previously examined. In our study, we reported that...

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