Article
The stoichiometry of the Escherichia coli Hfq protein bound to RNA.
RNA (New York, N.Y.) - 1 Mar 2011
Updegrove Taylor B, Correia John J, Chen Yanfeng, Terry Charles, Wartell Roger M
Abstract excerpt
The Escherichia coli RNA binding protein Hfq is involved in many aspects of post-transcriptional gene expression. Tight binding of Hfq to polyadenylate sequences at the 3' end of mRNAs influences exonucleolytic degradation, while Hfq binding to small noncoding RNAs (sRNA) and their targeted mRNAs facilitate their hybridization which in turn effects translation. Hfq binding to an A-rich tract in the 5' leader...
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