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Fetal Cell Microchimerism and Cancer: A Nexus of Reproduction, Immunology, and Tumor Biology

1 Jan 2011

Abstract excerpt

Fetal cell microchimerism (FCM) is the persistence of fetal cells in the maternal circulation and organs following pregnancy. Proposed hypotheses about the function of fetal cells in the pathogenesis of maternal cancer include promotion of tumorigenesis, protection by providing immunosurveillance, and participation in tissue repair. To date, studies of FCM and cancer have been primarily descriptive and...

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PMID: 21199793
DOI: 10.1158/0008-5472.can-10-0618

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