Article
Geographic variation of the major histocompatibility complex in Eastern Atlantic grey seals (Halichoerus grypus).
Molecular ecology - 1 Feb 2011
Cammen K, Hoffman J I, Knapp L A, Harwood J, Amos W
Abstract excerpt
Pathogen-driven balancing selection maintains high genetic diversity in many vertebrates, particularly in the major histocompatibility complex (MHC) immune system gene family, which is often associated with disease susceptibility. In large natural populations where subpopulations face different pathogen pressures, the MHC should show greater genetic differentiation within a species than neutral markers. We...
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