Article
Thyroid pathology in PTEN-hamartoma tumor syndrome: characteristic findings of a distinct entity.
Thyroid : official journal of the American Thyroid Association - 1 Feb 2011
Laury Anna Ray, Bongiovanni Massimo, Tille Jean-Christophe, Kozakewich Harry, Nosé Vânia
Abstract excerpt
BACKGROUND: Phosphatase and tensin homolog deleted on chromosome ten (PTEN)-hamartoma tumor syndrome (PHTS) is a complex disorder caused by germline inactivating mutations of the PTEN tumor suppressor gene. PHTS includes Cowden syndrome (CS), Bannayan-Riley-Ruvalcaba syndrome (BRRS), and Proteus-like syndromes. Affected individuals develop both benign and malignant tumors in a variety of tissues, including the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
