Article
Real-time quantitative polymerase chain reaction analysis of patients with refractory chronic periodontitis.
Journal of periodontology - 1 Jul 2011
Marconcini Simone, Covani Ugo, Barone Antonio, Vittorio Orazio, Curcio Michele, Barbuti Serena, Scatena Fabrizio, Felli Lamberto, Nicolini Claudio
Abstract excerpt
BACKGROUND: Periodontitis is a complex multifactorial disease and is typically polygenic in origin. Genes play a fundamental part in each biologic process forming complex networks of interactions. However, only some genes have a high number of interactions with other genes in the network and may, therefore, be considered to play an important role. In a preliminary bioinformatic analysis, five genes that showed a...
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