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Article

KATP channel mutations in congenital hyperinsulinism.

Seminars in pediatric surgery - 1 Feb 2011

Saint-Martin Cécile, Arnoux Jean-Baptiste, de Lonlay Pascale, Bellanné-Chantelot Christine

Abstract excerpt

Adenosine triphosphate (ATP)-sensitive potassium channels (K(ATP) channels) have a central role in the regulation of insulin secretion in pancreatic β cells. They are octameric complexes organized around the central core constituted by the Kir6.2 subunits. The regulation of the channel itself takes place on the sulfonylurea receptor-1 subunit. The channel opens and closes according to the balance between adenine...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21185999
DOI: 10.1053/j.sempedsurg.2010.10.012

Genes

ABCC8
KCNJ11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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