Article
Increased symptoms of attention deficit hyperactivity disorder and major depressive disorder symptoms in Nail-patella syndrome: potential association with LMX1B loss-of-function.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jan 2011
López-Arvizu Carmen, Sparrow Elizabeth P, Strube Michael J, Slavin Chris, DeOleo Caroline, James Justin, Hoover-Fong Julie, McIntosh Iain, Tierney Elaine
Abstract excerpt
Nail-Patella syndrome (NPS) is an autosomal dominant disorder that is the result of heterozygous loss-of-function mutations in LMX1B, coding for a LIM homeobox (LIM-HD) transcription factor. Analyses of lmx1b mutant mice have revealed the role of Lmx1b in the development of mesencephalic dopamine...
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