Article
Hepatocellular carcinoma with persistent hepatitis B virus infection shows unusual downregulation of Ras expression and differential response to Ras mediated signaling.
Journal of gastroenterology and hepatology - 1 Jan 2011
Bose Sujoy, Sakhuja Puja, Bezawada Lavanaya, Agarwal Anil K, Kazim Seyed N, Khan Luqman A, Sarin Shiv K, Ramakrishna Gayatri
Abstract excerpt
BACKGROUND AND AIM: Persistent infection with hepatitis B virus (HBV) is a major etiological risk factor for hepatocellular carcinoma (HCC). The host cellular components involved in the progression of the carcinoma are still unclear. In the present study we aimed to evaluate Ras mediated signalin...
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