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Article

Structural insight to mutated Y116S transthyretin by molecular dynamics simulation.

Indian journal of biochemistry & biophysics - 1 Aug 2010

Banerjee Avik, Bairagya Hridoy R, Mukhopadhyay Bishnu P, Nandi Tapas K, Bera Asim K

Abstract excerpt

Familial amyloidotic polyneuropathy (FAP) is strictly associated with point mutations of transthyretin (TTR) protein. The Tyr116-->Ser (Y116S) mutant TTR is an important amyloidogenic variant responsible for FAP. Structural dynamics of monomeric TR and its mutant (Y116S) may give some clue relati...

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Source

Identifiers

PMID: 21174946

Genes

FAP
TTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21174946-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Structural insight to mutated Y116S transthyretin by molecular dynamics simulation.PMID 21174946Read ↗

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