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Article

Inactivation of bb0184 , Which Encodes Carbon Storage Regulator A, Represses the Infectivity of Borrelia burgdorferi

21 Dec 2010

Abstract excerpt

The genome of Borrelia burgdorferi, the Lyme disease spirochete, encodes a homolog (the bb0184 gene product) of the carbon storage regulator A protein (CsrA(Bb)); recent studies reported that CsrA(Bb) is involved in the regulation of several infectivity factors of B. burgdorferi. However, the mechanism involved remains unknown. In this report, a csrA(Bb) mutant was constructed and complemented in an infectious...

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PMID: 21173314
DOI: 10.1128/iai.00871-10

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