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Article

A time course of hepcidin response to iron challenge in patients with HFE and TFR2 hemochromatosis.

Haematologica - 1 Apr 2011

Girelli Domenico, Trombini Paola, Busti Fabiana, Campostrini Natascia, Sandri Marco, Pelucchi Sara, Westerman Mark, Ganz Tomas, Nemeth Elizabeta, Piperno Alberto, Camaschella Clara

Abstract excerpt

BACKGROUND: Inadequate hepcidin production leads to iron overload in nearly all types of hemochromatosis. We explored the acute response of hepcidin to iron challenge in 25 patients with HFE-hemochromatosis, in two with TFR2-hemochromatosis and in 13 controls. Sixteen patients (10 C282Y/C282Y hom...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21173098
DOI: 10.3324/haematol.2010.033449
PMCID: PMC3069225

Genes

HFE
TFR2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21173098-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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