Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Plasmapheresis-induced clinical improvement in a patient with steroid-resistant nephrotic syndrome due to podocin (NPHS2) gene mutation.

Acta medica (Hradec Kralove) - 1 Jan 2010

Skálová Sylva, Podhola Miroslav, Vondrák Karel, Chernin Gil

Abstract excerpt

Podocin mutations (NPHS2 gene) are mostly responsible for steroid-resistant nephrotic syndrome (SRNS) of childhood onset. Patients with NPHS2 gene mutations do not respond to corticoids and other immunosuppressive agents; partial remission can be rarely induced by cyclosporin A. We present a boy, where SRNS was diagnosed within first year of life. By the age of 15 years, proteinuria reached 9000 mg/24 h,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Drug Resistance
Share to Glucocorticoids

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Intracellular Signaling Peptides and Proteins

Share to Membrane Proteins

Share to Methylprednisolone

Share to Mutation

Share to Nephrotic Syndrome

Source

Identifiers

PMID: 21171529
DOI: 10.14712/18059694.2016.76

Genes

NPHS2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Plasmapheresis-induced clinical improvement in a patient with steroid-resistant nephrotic syndrome due to podocin (NPHS2) gene mutation.PMID 21171529Read ↗

A case report of congenital nephrotic syndrome caused by new mutations of NPHS1.Semantic proximity Read ↗

NPHS2 gene in steroid-resistant nephrotic syndrome: prevalence, clinical course, and mutational spectrum in South-West Iranian children.Semantic proximity Read ↗

Cyclosporine A responsive congenital nephrotic syndrome with single heterozygous variants in NPHS1, NPHS2, and PLCE1.Semantic proximity Read ↗

Treatment and outcome of congenital nephrotic syndrome.Semantic proximity Read ↗

Clinical features and long-term outcome of nephrotic syndrome associated with heterozygous NPHS1 and NPHS2 mutations.Semantic proximity Read ↗

NPHS2 gene mutations in azerbaijani children with steroid-resistant nephrotic syndrome.Semantic proximity Read ↗

NPHS2 mutations in children with steroid-resistant nephrotic syndrome.Semantic proximity Read ↗

NPHS2 Mutations in Familial Steroid Resistant Nephrotic Syndrome in GazaSemantic proximity Read ↗

NPHS2 (podicin) mutations in Turkish children with idiopathic nephrotic syndrome.Semantic proximity Read ↗

NPHS2 (Podocin) mutations in nephrotic syndrome. Clinical spectrum and fine mechanisms.Semantic proximity Read ↗

Partial remission with cyclosporine A in a patient with nephrotic syndrome due to NPHS2 mutationSemantic proximity Read ↗

Molecular basis of steroid-resistant nephrotic syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.